Has anyone found a solution to this problem? I am having the exact same problem, and after several days of uninstalling HIS, reinstalling the IBM drivers and pulling my hair out, I am at a loss.
Funny thing is other DBA's can run a working package on their machine that does this, and on mine it fails. We found this after I continued to get this error working on a new package. This tells me it is definitely something on my machine, but I can't find it! Going to ODBC connections are not an option; the entire ETL structure we built for this data mart using this current approach.