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Network Infrastructure
LAN/WAN fails
Router/switch fails
DNS/WINS fails
Internet access fails
Etc.
In many ways, this category is just as important, if not more so, than server hardware. If your SQL Servers can't communicate with your users, they aren't of much use.
Electrical Power
Blackouts/Brownouts
Data center power failure
Area-wide power failure
City-wide power failure
Energy conservation restrictions (rolling blackouts)
This category is a no-brainer.
Scheduled Hardware/Software Upgrades/Patches
Hardware upgrades
Hardware driver upgrades
OS/Application software upgrades
OS/Application patches
SQL Server service packs/hotfixes
This category is an often forgotten source of SQL Server downtime. Hopefully, you can schedule downtime for this important area, unlike much downtime, which is unplanned.
Operating System
Bugs
Blue screens
Memory leaks
Security issues
While Window has gotten better over time, it still is not perfect and is subject to occasional problems. On the other hand, I have had SQL Servers up for six months, and longer, without any reboots.
SQL Server
Data corruption
Poor configuration
SQL Server itself can cause havoc, causing downtime. In fact, from personal experience, I have had more problems with SQL Server than with the operating system in regard to unexpected downtimes.
Human Errors
DBAs make mistakes (rarely, of course)
Developers make mistakes or write bad code
Users delete or corrupt data
Managers don’t provide necessary resources
These are some of the largest causes of unexpected downtime, but most of us don't want to talk about them. I wonder why?
Application Software
Applications fail
Applications corrupt data
Applications crash SQL Server
Applications can waste high amounts of SQL Server resources, preventing others from doing their work
Here, I am referring to the software used to access SQL Server. When application software fails, SQL Server often gets the blame, although unfairly. As a DBA, you need to take into consideration application software when planning for high availability.
Poor Tuning
Poor tuning uses up resources and can prevent users from doing their job.
Poor query design
Lack of indexes
Outdated statistics
Poor database design
Concurrency issues
Here's an area you may not have thought about. There are many performance tuning-related issues that can prevent users from accessing data when they want. While some DBAs don't consider performance tuning a high availability issue, it really is.