Changing published database question

Our vendor gave us a script to apply changes to their application and a database that is being published in transactional and snapshot replications. The script should add/modify tables, columns, etc.
Can anyone tell me how do I go with these changes? Do I just stop SQL agent, apply changes to the database and then re-start SQL agent, or there are some additional steps to be taken?
Thanks

If the scripts are modifyin the replicated tables then you can't add/remove column with ALTER TABLE script you have to use special procedure like sp_repladdcolumn...
Check the following article...
http://www.replicationanswers.com/AddColumn.asp