BizTalk Server 2009 will have full support for Windows Server 2008, SQL Server 2008, Visual Studio 2008 Service Pack 1, and .Net Framework 3.5 Service Pack 1. It will, for example, be able to run as a virtual machine in Hyper-V on a Windows Server 2008 machine, Kawasaki said. more at http://www.informationweek.com/news/windows/operatingsystems/showArticle.jhtml?articleID=210500383